Searchable abstracts of presentations at key conferences in endocrinology

ea0022p706 | Obesity | ECE2010

The influence of weight-loss induced by bariatric surgery on serum concentrations of novel metabolic regulators FGF-21 and FGF-19 in morbidly obese subjects

Haluzikova Denisa , Bartlova Marketa , Mraz Milos , Lacinova Zdena , Krizova Jarmila , Kavalkova Petra , Trachta Pavel , Michalsky David , Kasalicky Mojmir , Haluzik Martin

Objective: Fibroblast growth factor 19 (FGF-19) and FGF-21 are novel metabolic regulators that improve insulin resistence and obesity in rodents. The objective of this study was to explore whether changes in serum concentrations of FGF-19 and FGF-21 contribute to positive metabolic effects of weight loss induced by surgical treatment of obesity – sleeve gastrectomy (SG).Methods: Serum concentrations of FGF-19 and 21, adiponectin, resistin, fatty aci...